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Background We encountered a woman with vaginal cancer that was associated with complete uterine prolapse and complicated by severe intrauterine adhesions. In this case report, we describe the clinical course and successful treatment of this rare condition. Case presentation A 78-year-old woman (gravida 10, para 2, abortion 8) with a 10-year history of uterine prolapse presented for evaluation of bleeding from an ulceration on the surface of the irreducibly prolapsed uterus. Biopsy of a mass on her vaginal wall led to a diagnosis of keratinizing squamous cell carcinoma. Her history of eight abortion procedures had resulted in severe intrauterine adhesions, preventing tandem insertion and intracavitary brachytherapy. She was also ineligible for surgery under general anesthesia + chemotherapy because of her advanced age and presence of arrhythmia. Therefore, we devised an extensive treatment plan involving high-dose-rate interstitial brachytherapy. This treatment successfully eliminated the squamous cell carcinoma as confirmed by biopsy with no recurrence or severe late complications. Conclusions We found that high-dose-rate interstitial brachytherapy may be a very effective therapeutic strategy for this condition with few adverse effects.
Brachytherapy - Mayo Clinic
Toshiya MAASHI, Nihon University, Tokyo, Nichidai
Cervical cancer treatment in Mumbai
Cancer Treatment and Pelvic Health - A Womans Health
Kaplan-Meier curves demonstrating (A) improved local control (p =
Masahiro OKADA, Professor, Nihon University, Tokyo, Nichidai, Department of Radiology
Uterine Cancer - HealthyWomen
Complications of pelvic radiation in patients treated for gynecologic malignancies - Viswanathan - 2014 - Cancer - Wiley Online Library
Is there an Association between Vaginal Cancer and Genital Prolapse? A Data-Analysis and Review of Literature
Current Oncology, Free Full-Text
Vaginal SCC in Pelvic Organ Prolapse.pptx
Types of Pelvic Cancers - Body Harmony Physical Therapy
Treatment characteristics of early stage vaginal cancer patients (n = 10).
Masahiro OKADA, Professor, Nihon University, Tokyo, Nichidai, Department of Radiology