Transient rest restores functionality in exhausted CAR-T cells

Stem-like memory T cells are generated during hollow fiber perfusion-based expansion and enriched after cryopreservation in an automated modular cell therapy manufacturing process - Cytotherapy

PDF) Transient rest induces functional reinvigoration and epigenetic remodeling in exhausted CAR-T cells

Steering CAR T cell epigenetic programs by tweaking manufacturing protocol - ScienceDirect

Frontiers Mechanisms of CAR T cell exhaustion and current counteraction strategies

Small-Molecule Compounds Boost CAR-T Cell Therapy in Hematological Malignancies

Frontiers The current landscape of CAR T-cell therapy for solid tumors: Mechanisms, research progress, challenges, and counterstrategies

Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours. - Abstract - Europe PMC

Transient mTOR inhibition rescues 4-1BB CAR-Tregs from tonic

GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells - ScienceDirect

GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas

PDF) Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling

Clinical implications of T cell exhaustion for cancer

Pushing Past the Blockade: Advancements in T Cell-Based Cancer Immunotherapies. - Abstract - Europe PMC

Stem-like memory T cells are generated during hollow fiber

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