Slow, tight-binding inhibition of PDF by actinonin induces

Reaction catalysed by FAH and TS mimic inhibitors The tetrahedral

Slow, tight-binding inhibition of PDF by actinonin induces

Trapping Conformational States Along Ligand-Binding Dynamics of Peptide Deformylase: The Impact of Induced Fit on Enzyme Catalysis

7: Tight Binding Inhibition

6: Slow Binding Inhibitors

Frontiers Altered Mitochondrial Protein Homeostasis and Proteinopathies

Michel Desmadril's research works Université Paris-Saclay, Paris and other places

Trapping Conformational States Along Ligand-Binding Dynamics of Peptide Deformylase: The Impact of Induced Fit on Enzyme Catalysis

Full article: Atomic level and structural understanding of natural ligands inhibiting Helicobacter pylori peptide deformylase through ligand and receptor based screening, SIFT, molecular dynamics and DFT – a structural computational approach

Isabelle ARTAUD, Research Director, PhD, French National Centre for Scientific Research, Paris, CNRS, Chemistry and Biology Interdisciplinar Centre paris Descartes University france