Skin tissue regeneration for burn injury

The skin is the largest organ of the body, which meets the environment most directly. Thus, the skin is vulnerable to various damages, particularly burn injury. Skin wound healing is a serious interaction between cell types, cytokines, mediators, the neurovascular system, and matrix remodeling. Tissue regeneration technology remarkably enhances skin repair via re-epidermalization, epidermal-stromal cell interactions, angiogenesis, and inhabitation of hypertrophic scars and keloids. The success rates of skin healing for burn injuries have significantly increased with the use of various skin substitutes. In this review, we discuss skin replacement with cells, growth factors, scaffolds, or cell-seeded scaffolds for skin tissue reconstruction and also compare the high efficacy and cost-effectiveness of each therapy. We describe the essentials, achievements, and challenges of cell-based therapy in reducing scar formation and improving burn injury treatment.

Recent developments and advanced strategies for promoting burn

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Burn Wound Care Musculoskeletal Key

PDF) Skin tissue regeneration for burn injury

PDF] Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications

Pharmaceuticals, Free Full-Text

Skin regeneration, repair, and reconstruction: present and future

Application of nanomedicine and mesenchymal stem cells in burn injuries for the elderly patients - ScienceDirect

Spray-on skin' helps young man regenerate skin tissue - UCHealth Today

Polymers, Free Full-Text

Spray-on skin' helps young man regenerate skin tissue - UCHealth Today

Pharmaceuticals, Free Full-Text

Recent Advancements in Applications of Chitosan-based Biomaterials for Skin Tissue Engineering

Frontiers Skin Tissue Substitutes and Biomaterial Risk Assessment and Testing