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Difference Between Perimenopause and Menopause What is Perimenopause? Perimenopause is a period of gradual decline of the estrogen levels in the woman's body. Perimenopause is a transitional stage. It is a normal physiological stage occurring prior to the menopause. Perimenopause begins at a different age, usually at the beginning of the woman's 40s. However, it may start earlier or later.
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