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The human immune system is a highly complex network of cells, signals, and responses that is tightly regulated to ensure that the body can fight off infection without damaging its own tissues. Now, researchers from Japan report a new way in which the immune system protects lung tissue from viral infections.
Alveolar macrophages help CD8+ T cells go (anti-)viral
JCI Insight - β-Catenin signaling in alveolar macrophages enhances lung metastasis through a TNF-dependent mechanism
Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection - ScienceDirect
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Frontiers Nonclassical monocytes potentiate anti-tumoral CD8+ T cell responses in the lungs
Complement activation induces excessive T cell cytotoxicity in severe COVID-19 - ScienceDirect
Alveolar macrophage (AM) function during homeostasis or infection by
CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor - ScienceDirect
Frontiers Crosstalk Between Tumor-Associated Microglia/Macrophages and CD8-Positive T Cells Plays a Key Role in Glioblastoma
PDF] Memory CD8 T Cells: Orchestrators And Key Players Of, 50% OFF
Anti-inflammation macrophages and monocytes were recruited in the
Expansion of Cytotoxic CD4+ T cells in the lungs in severe COVID-19
Alveolar macrophages help CD8+ T cells go (anti-)viral|NARA Institute of Science and Technology